- Tablet Dissolution Testing Instruments
- Offline Automated Dissolution Systems
- Online Automated Dissolution Systems
- In-Situ Dissolution Testing (Coming Soon)
- Media Preparation
- UV/VIS Spectrometers
Tablet Disintegration Testing Instruments
Tablet disintegration testing instruments are widely used in the pharmaceutical industry to evaluate the disintegration characteristics of formulations and the quality control of different dosage forms.
Suppository Testing Instruments
This range of instruments to test the quality of suppositories, pessaries and creams includes disintegration and penetration testers.
Tablet Hardness Testing Instruments
Tablet hardness testing is used to test the breaking point and structural integrity of a tablet prior to storage, transportation, and handling before usage.
Ampoule Testing Instruments
Many liquid drugs are delivered in ampoules.We offer a fully DIN/ISO 9187 compliant solution to test the hardness of empty ampoules at line during production.
Tablet Friability Testing Instruments
Friability testing is used to test the durability of tablets during packing processes and transit. This involves repeatedly dropping a sample of tablets over a fixed time, using a rotating drum with a baffle.
Powder Testing Instruments
The Pharma Test powder testing product portfolio includes instruments to not only measure bulk density but also tap density and flowability.
Leak Testing Instruments
The leak test apparatus is used in the pharmaceutical industry to check the integrity of tablet strips, blister packs and small bottles.
PTS 3E
Suppository Disintegration Test Instrument
The PTS 3E Suppository and Pessaries Disintegration Tester is designed and manufactured
in compliance to the EP monograph <2.9.2.1/2.9.2.2> and the German DAB Pharmacopoeia.
The PTS 3E is used for the manual measurement of suppositories and pessaries
disintegration times.
The instrument meets the requirements of the valid EP and German DAB pharmacopoeia. According to the Pharmacopoeia monograph 3 samples are tested at the same time. The total testing period can be pre-set within a range of 1 minute to 10 hours. When used to test suppositories the sample baskets will turn automatically each 10 minutes through 180 degrees as specified in the relevant monograph.
>Fully EP <2.9.2> compliant
>Test 3 samples at the same time
>Test suppositories as well as pessaries
>GMP compliant stainless steel housing
ADVANTAGES
>Removable bath, sample holder and test baskets for easy cleaning
>Heating system is protected against any fat or grease intrusion
>Tubular heater and powerful circulation pump system for even temperature distribution
>IQ/OQ documents included free of charge
| Parameter | Specification |
| Display | LED Display |
| Keyboard | Function keys |
| Thermostat | Built-in 1000W heating tube and circulation pump, overheating protection, temperature adjustable within 30° to 40°C |
| Accuracy | ± 0.5 °C |
| Testing time | Programmable from 1 minute to 10 hours |
| Cycling time | Programmable from 1 to 10 minutes |
| Test stations | 3 |
| Instrument housing | Stainless steel to comply with GLP standards |
| Instrument dimensions | Approx. 720 x 280 x 360 mm (Length x Width x Height) |
| Packaging dimensions | Approx. 760 x 570 x 570 mm (Length x Width x Height) |
| Net / Gross weight | Approx. 22 / 28 kg |
Included in the Standard Scope of Supply
>PTS 3E Plexiglas-Water bath complete (part. no. 391-7140)
>PTS 3E POM toothed gear (part. no. 391-2601)
>PTS 3E spring (part. no. 391-1148)
>POM Plexiglass drive arm and basket support complete (part. no. 391-1142)
>Stainless steel basket for suppositories and pessaries (part. no. 391-7352)
>Glass cover plate to test vaginal ovals (part. no. 391-3002)
>Glass test rod (part. no. 391-3003)
SPT-6
Suppository Penetration Test Assembly
The SPT-6 Suppository Penetration Test assembly is used to determine the softening time of six samples at the same time. It is connected to a Pharma Test PTZ AUTO or PTZ-S tablet disintegration test instrument. The SPT-6 assembly can also be immersed into a suitable water bath. The SPT-6 is made in strict compliance with EP <2.9.22> Apparatus <A>. The assembly is placed into its own single position Plexiglas water bath. This way it is possible to use the SPT-6 in either a PTZ AUTO 1-4, PTZ AUTO 1EZ-4EZ or a PTZ-S tablet disintegration test instrument.
>Fully EP <2.9.22.1> Apparatus A compliant
>Test six samples at the same time
>Connect to any PTZ-S, DIST-3, PTZ AUTO 1-4 or PTZ AUTO 1EZ – 4EZ instrument
>Supply scope includes water bath and tubing connection to heating system of disintegration testing instrument
Advantages
>Fully automated detection of suppository softening time (with PTZ AUTO EZ only)
>Round, clear-view waterbath for excellent visibility of all samples
>Multi-purpose system: the disintegration testing instrument can still be used for regular tablet disintegration tests
>IQ/OQ documents included free of charge
| Parameter | Specification |
| Number of Glass Tubes | 6 glass tubes 5.2 mm diameter – 140 mm length |
| Number of Test Rods | 6 test rods, total weight each 30 ± 0.1g |
| Additional Equipment needed | Thermostat to heat the water bath, or PTZS/PTZAUTO Disintegration Test Instrument to connect the water bath |
| Packaging dimensions | Approx. 500 x 500 x 400 mm (width x depth x height) |
| Net / Gross Weight | Approx. 8 / 12 kg |
Included in the Standard Scope of Supply
>Glass tube for SPT-6 (part. no. 392-0010)
>Test rod for SPT-6 (part. no. 392-0011)
>Plexiglas water bath, without cover and tubing (part. no. 101-0215)
>Control thermometer 1HN11 -10/+50°C, not calibrated (part. no. 105-0801)
>Supporting shaft (part. no. 392-0100)
PTSW-0
Suppository Dissolution Test Cell (Rotating Dialysis Cell)
The PTSW-0 Suppository Dissolution Test Cell (Rotating Dialysis Cell) is placed into a standard USP type dissolution vessel which in turn is inserted into a standard tablet dissolution testing instrument to test the rate of dissolved active of suppositories and lipophilic carriers.
>Variable rotation speed, low speed settings using reduction gear
>Useable with every Pharma Test PTWS
Advantages
>Can be used in a common dissolution bath having a suitable drive system (drive shaft design made to fit into Pharma Test dissolution bath only)
>Easy to operate, set-up and remove for cleaning
| Parameter | Specification |
| Cell rotation speed | 5 – 60 rpm |
| Drive gear | Speed reduction ratio 4:1 |
| Filter membrane | Typical: Millipore Durapor HPVL 0.45 µm |
Included in the Standard Scope of Supply
>Complete PTSW-0 Suppository Dissolution Test Cell (part. no. 39-00502)
>One set of filter membrane (part no. 500-0503-50)
