ENDOTOXIN TEST RELATED PRODUCTS
CONTROL STANDARD ENDOTOXIN
Our Control Standard Endotoxin (CSE) is a lyophilized product composed of a 500-ng vial of endotoxin, purified from E. coli UKT-B strain that serves as an accurate and dependable standard for endotoxin testing.
KEY FEATURES
- Endotoxin derived from E. coli UKT-B
- Can be used to prepare controls and standard curves
- Potency of CSE supplied to match each lot of LAL
- Reconstituted CSE can be stored at 2–10°C for 1 month
LPS FOR ENDOTOXIN INDICATORS
The LPS for Endotoxin Indicator is composed of E. coli O55:B5 (>100,000 EU/vial) and serves as a stock solution to prepare multiple endotoxin indicators for depyrogenation validation studies. The prepared endotoxin indicators may be tested using reagents from our PYROSTAR™ ES-F series.
KEY FEATURES
- E. coli 055:B5 (> 100,000 EU/vial)
- Can make multiple endotoxin indicators from one vial
- Used for dry heat oven validation studies
ES-BUFFER
The ES Buffer is an endotoxin-specific buffer that is ideal for untreated LAL. Though all LAL reagents produced by FUJIFILM Wako LAL are endotoxin-specific, other commercially available LAL reagents are not. Without this buffer, tests can present a potential false positive when trying to determine the endotoxin concentration in the sample.
The ES Buffer works by adding a large amount of carboxymethylated curdlan (CMC) to LAL, thus preventing the activation of LAL by glucan. The presence of large amounts of glucan does not interfere with the quantitation of endotoxin. FUJIFILM Wako first made use of these findings by developing this endotoxin-specific buffer, which contains high concentrations of CMC. When the ES Buffer is used to reconstitute LAL, reagent becomes endotoxin-specific.
KEY FEATURES
- Each vial has solution for use in reconstituting a max of 5.2 mL of reagent
- Ideal for use in reconstituting any LAL that has the potential to react with glucans, thus making an endotoxin-specific reagent
ENDOTOXIN EXTRACTING SOLUTION
Traditionally, water or saline solution has been used to extract endotoxin in tests involving medical devices and equipment; however, the efficacy of this extraction method is debated. In order to provide our customers with a more reliable method for medical device testing, FUJIFILM Wako has developed an endotoxin-free solution containing human serum albumin (HSA) that is capable of extracting endotoxins that cannot be extracted in water or saline solution.
Key Features
- Capable of extracting endotoxins from surfaces that are unable to be extracted in water or saline
- Recommended for use in endotoxin testing on equipment and devices that may come into contact with fluids containing blood or protein
