Endotoxin Testing Services
PYROSTAR™ ES-F SERIES
PYROSTAR™ ES-F Multi-Test
This multi-test vial is designed to be used with the water bath, heat block or the Toxinometer®. With this configuration, the user dispenses 0.1 mL of dissolved LAL reagent into the appropriate reaction tube, then adding in 0.1 mL of the sample. This multi-test vial is ideal for a user testing a larger number of samples.
KEY FEATURES
- Endotoxin-specific reagent avoids false positive results from (1→3)-β-D-glucan
- Dual-purpose reagent can perform either a gel clot or kinetic turbidimetric assay (KTA)
- Gel clot sensitivities range from 0.015 to 0.25 EU/mL; kinetic turbidimetric quantitative range from 0.001 to 10 EU/mL
- Due to its high sensitivity, chances of interference are reduced
- Facilitates an easier transition from gel clot to KTA
PYROSTAR™ ES-F Single 25 Test Kit
Single-test vials come with pre-dispensed LAL reagent for a single measurement. This configuration is used by adding 0.2 mL of the sample directly to the reaction vial containing the lyophilized reagent. This single-test vial is designed to be used with our Toxinometer® Measurement System (Toxinometer®) to assist labs transitioning from a gel clot to a kinetic turbidimetric methodology. The single-test configuration is ideal to assay a small number of samples or for a less-experienced user.
KEY FEATURES
- Endotoxin-specific reagent avoids false positive results from of (1→3)-β-D-glucan
- Gel clot sensitivities include 0.015EU/ml, 0.03 EU/mL, 0.125 EU/mL and 0.25 EU/mL
- KTA quantitative range from 0.001 to 10 EU/mL
- Can be used with the traditional water bath or heat block.
- Can be used with the Toxinometer® to facilitate an easier transition from gel clot to KTA
PYROSTAR™ ES-F/Plate Test Kit
This multi-test vial is designed to be used with the microplate reader. To use this configuration, dispense 0.05 mL of the sample into microplate following 0.05 mL of dissolved LAL reagent. This assay is ideal for testing a larger number of samples in one run.
KEY FEATURES
- Endotoxin-specific reagent avoids false positive results from glucans
- Available in 2.0 mL volume, which equates to approximately 40 tests per vial and 5.2 mL volume, which equates to 100 tests per vial
- KTA quantitative range from 0.01 to 10 EU/mL
Limulus Color KY Series
Limulus Color KY Multi Test
This multi-test vial is designed to be used with the Toxinometer® or a microplate reader.
To use this configuration with a microplate reader, dispense 0.05 mL of the sample into a microplate containing 0.05 mL of dissolved LAL reagent. When utilizing the Toxinometer®, the user dispenses 0.1 mL of dissolved LAL reagent into the appropriate reaction tube followed by 0.1 mL of the sample. The multi-test vial is ideal for a user with a larger number of samples or products that are turbid.
KEY FEATURES:
- Reagent reacts with endotoxin over a wide range of its concentrations
- Reduces the chance of interfering factors due to high sensitivity
- Can be used with Toxinometer® or microplate reader
- KCA quantitative range detection limit of 0.0005 – 5 EU/mL
- The sample size is 0.1 mL when used with tube reader; 0.05 mL sample size when used with microplate reader
Limulus Color KY Single Test
Limulus Color KY single-test vials come with pre-dispensed LAL reagent for a single measurement. This configuration is used by adding 0.2 mL of the sample directly to the reaction vial containing the lyophilized reagent. This single-test vial is ideal for user testing a smaller number of samples or one that is less-experienced.
KEY FEATURES
- KCA quantitative range detection limit of 0.0002- 2 EU/mL
- Reagent reacts with endotoxin in a wide range of its concentrations
- High sensitivity to reduce the chance of interfering factors
- Can be used with Toxinometer®
- Reduces the chance of contamination and no wasted reagent during testing
PS Single Test
Limulus PS Single Test
The Limulus PS Single Test is composed of LAL endotoxin-specific single-test vials and an affinity resin suspension called PyroSep™, designed to overcome any product interference by adsorbing potential endotoxin in samples while washing away the inhibitory components. When using this product, the endotoxin in the sample is adsorbed onto a capillary column filled with PyroSep™ (an affinity adsorbent with histidine bound to a water-insoluble support via a spacer). Inhibitory substances contained in the sample are washed away, allowing the adsorbed endotoxin to be measured with the single-test format LAL reagent.
KEY FEATURES
- Endotoxin-specific reagent avoids false positive results from glucans
- This kit is in single test configuration to avoid contamination
- KTA quantitation for this product is performed on Toxinometer®
- Allows endotoxin-specific measurement in samples that typically have inhibitory components: ethanol, silicone oil, soybean oil, olive oil, stearic acid, egg yolk lecithin, oil-adjuvanted vaccine, albumin products, coagulation factor products (factor 8), interferon formulation, antithrombin III, immunoglobulin product and other ethanol-soluble samples
